The Wolbachia method is a biological method that utilises the Wolbachia bacteria to control the spread of mosquito-borne diseases, particularly dengue fever. * Wolbachia naturally infects some insect species, but not Aedes aegypti mosquitoes, the primary vector for dengue fever transmission. Scientists introduce Wolbachia into Aedes aegypti populations.  Wolbachia reduces the ability of these mosquitoes to transmit dengue virus.  * As Wolbachia spreads through the mosquito population, it can significantly reduce the incidence of dengue fever.  * This method offers a natural and sustainable approach to controlling dengue fever, a major public health concern in tropical and subtropical regions.